Fibroblast Growth Factor 1 (FGF-1), human, active


SKU: 03-003 Research Area: , Applications:


FGF-1 (acidic FGF) is a member of the fibroblast growth factor (FGF) family, which binds heparin. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion (ref.).



  1. Use as a supplement in serum-free or reduced serum media for culture of mammalian cells
  2. Studies of the human FGF-1 receptor, transmembrane signaling and protein phosphorylation
  3. Western blotting control for anti-EGF-1 antibodies
  4. Widely used in cosmetics, such as whitening, anti-wrinkle, anti-aging, etc.



Product: Full length recombinant mature FGF-1 (15.8 kDa, 140 amino acids) expressed in E. coli.

Activity: The ED50 as determined by a cell proliferation assay using MTS assay kit (Cell Titer 96,

Promega) with Balb/c 3T3 cells was < 10 pg/ml, corresponding to a specific activity of < 1 x 108 units/mg.

Purity: >98% as determined by SDS-PAGE (CBB staining)

Form: 2.0 mg/ml in PBS (10mM Na-phosphate, 150mM NaCl) pH7.2, 50% glycerol, filter-sterilized

Storage: -20°C or for long-term storage, -70°C


Data Link: Gene ID: 2246,  Gene Sequence: BC032697,

Amino Acid Sequence: AAH32697


Reference Zakrzewska M et al (2008) “ FGF-1: from biology through engineering to potential medical applications.” Review Crit Rev Clin Lab Sci

45: 91-135PMID: 18293181

Fig.1 SDS-PAGE of human FGF-1

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03-003_03222018 application/pdf 179 KB

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